Human-Associated Extended-Spectrum β-Lactamase in the Antarctic

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Human-associated extended-spectrum β-lactamase in the Antarctic.

Escherichia coli bacteria with extended-spectrum β-lactamase (ESBL) type CTX-M resistance were isolated from water samples collected close to research stations in Antarctica. The isolates had bla(CTX-M-1) and bla(CTX-M-15) genotypes and sequence types (ST) indicative of a human-associated origin. This is the first record of ESBL-producing enterobacteria from Antarctica.

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Acknowledgments We dedicate this work to the late Andrew Spielman, our coauthor and beloved mentor. We thank J. Rivero, I. Pérez, M. Méndez, I. Matheus, M. Aguiar de Bracho, I. Carreño, J.M. Hernández, A. Nagy, A. Suarez, N. Moncada, M. Kilpatrick, E. Rodriguez, E. Marquez, E. Marian, B. Hernández; C. Rivero-Blanco, M. Azar, J. Rodriguez, H. Montañez, F. Alfonzo, and G. Rangel for their contrib...

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1. Threlfall EJ. Epidemic Salmonella typhimurium DT104 – a truly international epidemic clone. J Antimicrob Chemother. 2000;46:7–10. 2. Lawson AJ, Desai M, O’Brien SJ, Davies RH, Ward LR, Threlfall EJ. Molecular characterisation of an outbreak strain of multiresistant Salmonella enterica serovar Typhimurium DT104 in the UK. Clin Microbiol Infect. 2004;10:143–7. 3. Briggs CE, Fratamico PM. Molec...

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ژورنال

عنوان ژورنال: Applied and Environmental Microbiology

سال: 2012

ISSN: 0099-2240,1098-5336

DOI: 10.1128/aem.07320-11